According to Jaime Montilla:

Hacienda Fortuna already operated by 1834 when it was owned by Manuel Antonio del Toro (1776-1836) and Esteban Domenech who also owner the nearby Hacienda Unión.  By 1841 it was owned by Domenech & Guilbee, a partnership formed by Esteban Domenech and Jaime Guilbee Fenerign, a British Immigrant who came to Puerto Rico in 1821 and established residence in Ponce in 1829.  

Guilbee was hired by Domenech and del Toro to install a windmill at Hacienda Fortuna, which mill proved to be inefficient.  History is not clear if he was retained as administrator, but after the death of Manuel Antonio del Toro in 1836, he married his widow Rosa Loudon Gouden thus becoming 25% owner of Hacienda Fortuna, participation he later increased.  
 Beginning in the 1850s and until 1873, Hacienda Fortuna was owned by Guilbee and Manuel Ferrer, owner of haciendas Cintrona, Potala and Pastillo in Juana Diaz.  Hacienda Fortuna was acquired in 1877 by Juan Forgas Bayo (ca. 1810-1885), a resident of Barcelona, Spain who also had ownership in a Spanish shipping company and whose legal representative on the island was his Spanish immigrant nephew José Gallart Forgas (1829-1898).  Gallart Forgas arrived in Puerto Rico in 1842 and after a few years also owned Hacienda Luciana, Hacienda Cristina, Hacienda Serrano and Reparada Sugar Mill in Ponce, named Reparada in honor of his mother Reparada Forgas Bayo.

In 1877 under Gallart Forgas leadership, Hacienda Fortuna was converted into a Central Sugar mill.  It was Gallart who in 1885 commissioned Francisco Oller, a very well known local artist to do the oil painting of Fortuna shown below, which is on exhibit at the Brooklyn Museum.
  Upon his death in 1898, Gallart heirs included his second wife Mercedes Folch Parellada whom he married after the death of his first wife Julia Dubocq Roux in 1885.  The estate continued to operate the sugar mill until 1904 when it was acquired by the Compagnie des Sucreries de Porto Rico.  This company was owned by a group of Frenchmen headed by M. Manoury whose name was universally well known in the industry and which group included Mateo Luchetti Tristani, the son of Corsican immigrants and first cousin of Mateo Luchetti Piccioni owner of Ingenio Grande/Quebrada Palmas.  By 1905, its French owners had installed the first portable track and light engine in Puerto Rico.  They also were the first mill to use the Naudet Process which combined milling, difusion and clarification in one operation.  The process though, appeared not to be successfull due to high fuel cost. 

In 1909 Central Fortuna was acquired by the South Porto Rico Sugar Co., owners of Guanica Centrale, from the Compagnie des Sucreries de Porto Rico for $1,750,000, at the time the biggest sugar estate transaction in Puerto Rico.  The Louisiana Planter and Sugar Manufacturer in its edition of December 4, 1909 states that “a cyclone has been doing business around the island and as a result the 1910 cane crop has suffered severly.  While the cyclone itself did not approach the island its effects have been felt heavily and floods have done a great deal of damage.  Hacienda Fortuna of Ponce, suffered severely, the water in the Central attaining a depth of over a meter, and nearly all of the livestock was drowned, all the small bridges around the Central washed away and a goodly part of its railroad line washed out.”  

In that same edition it is reported that Guanica Central “is utilizing a goodly part of the machinery of the old Fortuna estate which was in A-1 condition, and all of the cane formerly ground at Fortuna will be ground this year at Guanica.  Central Fortuna, however, is being refitted throughout and expects to do its own grinding in 1911.”

The purchase by the South Porto Rico Sugar Co. turned out to be a disaster and ended up with the closure of Central Fortuna in 1914.  Its sugarcane was then processed at Guanica Centrale until 1921, when as the result of labor disputes, they were forced to sell the sugarcane harvested in the lands of Fortuna to Central Aguirre.  Fortuna’s machinery was dismantled and shipped to the Dominican Republic where it was installed at Central Romana sugar factory.
 Fortuna was only about 2¼ miles from Central Mercedita which was a much larger sugar mill.  It was also only about 1⅛ mile from Central Boca Chica both at one time owned by the Serrallés family.  Today, the only remains from Fortuna’s days as a hacienda is the brick smoke stack pictured below, which is approximately 800 m south of the smoke stack of the Central Sugar mill.

We have no production data for Fortuna but understand its best production year was its last year in operation; 1914 with 10,000 tons of sugar.[ref]”Central Fortuna.” jaimemontilla.com. Accessed 8/29/21[/ref]